Céline. Héraud, et.al., Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice., Neurobiology of disease, 2014, 62

http://rdf.ncbi.nlm.nih.gov/pubmed/24076100

Céline. Héraud, et.al., Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice., Neurobiology of disease, 2014, 62

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0
  http://metadb.riken.jp/0002083IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgAPPSwFlLonPSEN1M146LL286V6799Vas
• amyloid beta deposits_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0003329IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd
• amyloid beta deposits_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0
  http://metadb.riken.jp/0003329IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgAPPSwFlLonPSEN1M146LL286V6799Vas
• decreased body weight_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0001262IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd
• abnormal neurite morphology_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0008415IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd
• impaired coordination_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0001405IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd
• decreased hippocampus pyramidal cell number_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0009971IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd
• decreased brain weight_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0002175IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd
• neurofibrillary tangles_Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0003214IC57BL6C57BL6JCBASJLTgThy1MAPT30Schd0TgThy1MAPT30Schd
• neurofibrillary tangles_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0003214IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd
• premature death_Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0,Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0002083IC57BL6C57BL6JCBASJLTgAPPSwFlLonPSEN1M146LL286V6799Vas0TgThy1MAPT30Schd0TgAPPSwFlLonPSEN1M146LL286V6799VasTgThy1MAPT30Schd
• impaired coordination_Tg(Thy1-MAPT*)30Schd/0
  http://metadb.riken.jp/0001405IC57BL6C57BL6JCBASJLTgThy1MAPT30Schd0TgThy1MAPT30Schd