abnormal myocardial trabeculae morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>

http://metadb.riken.jp/0002189EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc

abnormal myocardial trabeculae morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• myosin, light polypeptide 2, regulatory, cardiac, slow
  http://metadb.riken.jp/db/mgi_rdf/MGI:97272
• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Myl2<+>|Nkx2-5<tm1Krc>|Myl2<tm1(cre)Krc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129/Sv * Black Swiss) or (involves: 129/Sv * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal myocardial trabeculae morphology
  http://purl.obolibrary.org/obo/MP_0002189

文献

http://purl.org/net/cito/citesAsAuthority

• Mohammad. Pashmforoush, et.al., Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block., Cell, 2004, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/15109497