Mohammad. Pashmforoush, et.al., Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block., Cell, 2004, 117

http://rdf.ncbi.nlm.nih.gov/pubmed/15109497

Mohammad. Pashmforoush, et.al., Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block., Cell, 2004, 117

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nkx2-5<tm1Krc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3042511
• Tg(NPPA-Bmp10)1Krc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043003

class

http://purl.org/net/cito/citesAsAuthority

• Nkx2-5<tm1Krc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3042511
• Tg(NPPA-Bmp10)1Krc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043003

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cardiac hypertrophy_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0001625EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• abnormal impulse conducting system morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0004123EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• abnormal atrioventricular bundle morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0004117EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• hydrops fetalis_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0002192EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• cardiac interstitial fibrosis_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0005608EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• edema_Tg(NPPA-Bmp10)1Krc/0
  http://metadb.riken.jp/0001785NSTgNPPABmp101Krc0TgNPPABmp101Krc
• perinatal lethality, incomplete penetrance_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0011090EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• abnormal myocardial trabeculae morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0002189EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• abnormal atrioventricular node morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0004114EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• abnormal myocardial fiber morphology_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0000278EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• thin ventricular wall_Tg(NPPA-Bmp10)1Krc/0
  http://metadb.riken.jp/0000280NSTgNPPABmp101Krc0TgNPPABmp101Krc
• thin interventricular septum_Tg(NPPA-Bmp10)1Krc/0
  http://metadb.riken.jp/0010725NSTgNPPABmp101Krc0TgNPPABmp101Krc
• abnormal myocardial trabeculae morphology_Tg(NPPA-Bmp10)1Krc/0
  http://metadb.riken.jp/0002189NSTgNPPABmp101Krc0TgNPPABmp101Krc
• atrioventricular block_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0010519EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc
• dilated cardiomyopathy_Myl2<tm1(cre)Krc>/Myl2<+>,Nkx2-5<tm1Krc>/Nkx2-5<tm1Krc>
  http://metadb.riken.jp/0002795EI129SvBlackSwissorI129SvC57BL6Myl2tm1creKrcMyl2Nkx25tm1KrcNkx25tm1KrcMyl2Nkx25tm1KrcMyl2tm1creKrc