abnormal long term potentiation_Psen1<tm1Vln>/Psen1<tm1Vln>,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0

http://metadb.riken.jp/0002207IFVBNPsen1tm1VlnPsen1tm1VlnTgThy1APPLon2Vln0TgThy1cre1Vln0Psen1tm1VlnTgThy1cre1VlnTgThy1APPLon2Vln

abnormal long term potentiation_Psen1<tm1Vln>/Psen1<tm1Vln>,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• presenilin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202717
• transgene insertion 1, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684622
• transgene insertion 2, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717495

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Psen1<tm1Vln>/Psen1<tm1Vln>,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Psen1<tm1Vln>|Tg(Thy1-cre)1Vln|Tg(Thy1-APPLon)2Vln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal long term potentiation
  http://purl.obolibrary.org/obo/MP_0002207

文献

http://purl.org/net/cito/citesAsAuthority

• Ilse. Dewachter, et.al., Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/11978821