muscular atrophy_Mnx1<tm4(cre)Tmj>/Mnx1<+>,Tardbp<tm1.1Ckjs>/Tardbp<tm1.2Cjks>

http://metadb.riken.jp/0002269I129S1SvC57BL6JMnx1tm4creTmjMnx1Tardbptm11CkjsTardbptm12CjksMnx1Tardbptm11CkjsMnx1tm4creTmjTardbptm12Cjks

muscular atrophy_Mnx1<tm4(cre)Tmj>/Mnx1<+>,Tardbp<tm1.1Ckjs>/Tardbp<tm1.2Cjks>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• motor neuron and pancreas homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109160
• TAR DNA binding protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387629

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mnx1<tm4(cre)Tmj>/Mnx1<+>,Tardbp<tm1.1Ckjs>/Tardbp<tm1.2Cjks>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mnx1<+>|Tardbp<tm1.1Ckjs>|Mnx1<tm4(cre)Tmj>|Tardbp<tm1.2Cjks>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• muscular atrophy
  http://purl.obolibrary.org/obo/MP_0002269

文献

http://purl.org/net/cito/citesAsAuthority

• Lien-Szu. Wu, et.al., Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice., The Journal of biological chemistry, 2012, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/22718760