abnormal nervous system electrophysiology_Htr2c<tm2Jke>/Y,Tg(Pomc1-cre)16Lowl/0,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0002272I129S6SvEvTac129X1SvJC57BL6FVBNHtr2ctm2JkeYTgPomc1cre16Lowl0GtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorHtr2ctm2JkeGtROSA26SorTgPomc1cre16LowlGtROSA26Sortm14CAGtdTomatoHze

abnormal nervous system electrophysiology_Htr2c<tm2Jke>/Y,Tg(Pomc1-cre)16Lowl/0,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• 5-hydroxytryptamine (serotonin) receptor 2C
  http://metadb.riken.jp/db/mgi_rdf/MGI:96281
• transgene insertion 16, Bradford B Lowell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3640615

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Htr2c<tm2Jke>/Y,Tg(Pomc1-cre)16Lowl/0,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Htr2c<tm2Jke>|Gt(ROSA)26Sor<+>|Tg(Pomc1-cre)16Lowl|Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal nervous system electrophysiology
  http://purl.obolibrary.org/obo/MP_0002272

文献

http://purl.org/net/cito/citesAsAuthority

• Eric D. Berglund, et.al., Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis., The Journal of clinical investigation, 2013, 123
  http://rdf.ncbi.nlm.nih.gov/pubmed/24177424