abnormal diaphragm morphology_Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<+>,Tg(Tek-cre)1Ywa/0

http://metadb.riken.jp/0002279I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeRobo4tm1KzhRobo4TgTekcre1Ywa0TgTekcre1YwaNdst1tm1JeRobo4tm1KzhRobo4

abnormal diaphragm morphology_Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<+>,Tg(Tek-cre)1Ywa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104719
• transgene insertion 1, Masashi Yanagisawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450309
• roundabout guidance receptor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921394

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<+>,Tg(Tek-cre)1Ywa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tek-cre)1Ywa|Ndst1<tm1Je>|Robo4<tm1Kzh>|Robo4<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal diaphragm morphology
  http://purl.obolibrary.org/obo/MP_0002279

文献

http://purl.org/net/cito/citesAsAuthority

• Bing. Zhang, et.al., Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia., The Journal of clinical investigation, 2014, 124
  http://rdf.ncbi.nlm.nih.gov/pubmed/24355925