Bing. Zhang, et.al., Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia., The Journal of clinical investigation, 2014, 124

http://rdf.ncbi.nlm.nih.gov/pubmed/24355925

Bing. Zhang, et.al., Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia., The Journal of clinical investigation, 2014, 124

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal vascular development_Robo4<tm1Kzh>/Robo4<tm1Kzh>
  http://metadb.riken.jp/0000259IC57BL6Robo4tm1KzhRobo4tm1KzhRobo4tm1Kzh
• abnormal septum transversum morphology_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0012252I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• abnormal vascular development_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000259I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• diaphragmatic hernia_Ndst1<tm1Je>/Ndst1<tm1Je>,Slit3<tm1.1Dor>/Slit3<+>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003924I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeSlit3tm11DorSlit3TgTekcre1Ywa0Ndst1tm1JeSlit3tm11DorTgTekcre1YwaSlit3
• abnormal tendon collagen fibril morphology_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0011643I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• abnormal central tendon morphology_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0012061I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• decreased angiogenesis_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0005602I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• decreased angiogenesis_Robo4<tm1Kzh>/Robo4<tm1Kzh>
  http://metadb.riken.jp/0005602IC57BL6Robo4tm1KzhRobo4tm1KzhRobo4tm1Kzh
• abnormal diaphragm morphology_Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<+>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0002279I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeRobo4tm1KzhRobo4TgTekcre1Ywa0TgTekcre1YwaNdst1tm1JeRobo4tm1KzhRobo4
• diaphragmatic hernia_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003924I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• hypoxia_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0005039I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• abnormal diaphragm morphology_Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<tm1Kzh>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0002279I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeRobo4tm1KzhRobo4tm1KzhTgTekcre1Ywa0TgTekcre1YwaRobo4tm1KzhNdst1tm1Je
• abnormal blood vessel morphology_Slit3<tm1.1Dor>/Slit3<tm1.1Dor>
  http://metadb.riken.jp/0001614I129S1SvC57BL6Slit3tm11DorSlit3tm11DorSlit3tm11Dor
• diaphragmatic hernia_Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<tm1Kzh>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003924I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeRobo4tm1KzhRobo4tm1KzhTgTekcre1Ywa0TgTekcre1YwaRobo4tm1KzhNdst1tm1Je
• herniated liver_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010912I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• abnormal vascular development_Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<tm1Kzh>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000259I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeRobo4tm1KzhRobo4tm1KzhTgTekcre1Ywa0TgTekcre1YwaRobo4tm1KzhNdst1tm1Je
• abnormal vascular development_Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<+>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000259I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeRobo4tm1KzhRobo4TgTekcre1Ywa0TgTekcre1YwaNdst1tm1JeRobo4tm1KzhRobo4
• abnormal diaphragm morphology_Robo4<tm1Kzh>/Robo4<tm1Kzh>
  http://metadb.riken.jp/0002279IC57BL6Robo4tm1KzhRobo4tm1KzhRobo4tm1Kzh
• abnormal central tendon morphology_Slit3<tm1.1Dor>/Slit3<tm1.1Dor>
  http://metadb.riken.jp/0012061I129S1SvC57BL6Slit3tm11DorSlit3tm11DorSlit3tm11Dor
• diaphragmatic hernia_Slit3<tm1.1Dor>/Slit3<tm1.1Dor>
  http://metadb.riken.jp/0003924I129S1SvC57BL6Slit3tm11DorSlit3tm11DorSlit3tm11Dor
• decreased endothelial cell proliferation_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0012201I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• abnormal diaphragm morphology_Slit3<tm1.1Dor>/Slit3<tm1.1Dor>
  http://metadb.riken.jp/0002279I129S1SvC57BL6Slit3tm11DorSlit3tm11DorSlit3tm11Dor
• thin diaphragm muscle_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000761I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa
• diaphragmatic hernia_Ndst1<tm1Je>/Ndst1<tm1Je>,Slit3<tm1.1Dor>/Slit3<tm1.1Dor>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003924I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeSlit3tm11DorSlit3tm11DorTgTekcre1Ywa0TgTekcre1YwaNdst1tm1JeSlit3tm11Dor
• diaphragmatic hernia_Ndst1<tm1Je>/Ndst1<tm1Je>,Robo4<tm1Kzh>/Robo4<+>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0003924I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeRobo4tm1KzhRobo4TgTekcre1Ywa0TgTekcre1YwaNdst1tm1JeRobo4tm1KzhRobo4
• abnormal diaphragm morphology_Ndst1<tm1Je>/Ndst1<tm1Je>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0002279I129S1Sv129X1SvJC57BL6SJLNdst1tm1JeNdst1tm1JeTgTekcre1Ywa0Ndst1tm1JeTgTekcre1Ywa