abnormal spleen white pulp morphology_Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?

http://metadb.riken.jp/0002357I129SSvEvKmt2atm1ThrKmt2aMllt3tm2ThrMllt3TgLckcre1ThrKmt2aMllt3tm2ThrTgLckcre1ThrKmt2atm1ThrMllt3

abnormal spleen white pulp morphology_Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lysine (K)-specific methyltransferase 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:96995
• myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917372
• transgene insertion 1, Terence H Rabbitts
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584020

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kmt2a<+>|Mllt3<tm2Thr>|Tg(Lck-cre)1Thr|Kmt2a<tm1Thr>|Mllt3<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal spleen white pulp morphology
  http://purl.obolibrary.org/obo/MP_0002357

文献

http://purl.org/net/cito/citesAsAuthority

• Lesley F. Drynan, et.al., Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis., The EMBO journal, 2005, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/16096649