Lesley F. Drynan, et.al., Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis., The EMBO journal, 2005, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/16096649

Lesley F. Drynan, et.al., Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis., The EMBO journal, 2005, 24

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged spleen_Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?
  http://metadb.riken.jp/0000691I129SSvEvKmt2atm1ThrKmt2aMllt3tm2ThrMllt3TgLckcre1ThrKmt2aMllt3tm2ThrTgLckcre1ThrKmt2atm1ThrMllt3
• abnormal spleen red pulp morphology_Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?
  http://metadb.riken.jp/0002356I129SSvEvKmt2atm1ThrKmt2aMllt3tm2ThrMllt3TgLckcre1ThrKmt2aMllt3tm2ThrTgLckcre1ThrKmt2atm1ThrMllt3
• increased leukemia incidence_Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?
  http://metadb.riken.jp/0002026I129SSvEvKmt2atm1ThrKmt2aMllt3tm2ThrMllt3TgLckcre1ThrKmt2aMllt3tm2ThrTgLckcre1ThrKmt2atm1ThrMllt3
• abnormal spleen white pulp morphology_Lmo2<tm2(cre)Thr>/Lmo2<+>,Kmt2a<tm1Thr>/Kmt2a<+>,Mllt1<tm1Thr>/Mllt1<+>
  http://metadb.riken.jp/0002357I129SSvEvLmo2tm2creThrLmo2Kmt2atm1ThrKmt2aMllt1tm1ThrMllt1Kmt2atm1ThrMllt1Lmo2Mllt1tm1ThrLmo2tm2creThrKmt2a
• enlarged spleen_Lmo2<tm2(cre)Thr>/Lmo2<+>,Kmt2a<tm1Thr>/Kmt2a<+>,Mllt1<tm1Thr>/Mllt1<+>
  http://metadb.riken.jp/0000691I129SSvEvLmo2tm2creThrLmo2Kmt2atm1ThrKmt2aMllt1tm1ThrMllt1Kmt2atm1ThrMllt1Lmo2Mllt1tm1ThrLmo2tm2creThrKmt2a
• increased hemolymphoid system tumor incidence_Lmo2<tm2(cre)Thr>/Lmo2<+>,Kmt2a<tm1Thr>/Kmt2a<+>,Mllt1<tm1Thr>/Mllt1<+>
  http://metadb.riken.jp/0010296I129SSvEvLmo2tm2creThrLmo2Kmt2atm1ThrKmt2aMllt1tm1ThrMllt1Kmt2atm1ThrMllt1Lmo2Mllt1tm1ThrLmo2tm2creThrKmt2a
• abnormal spleen white pulp morphology_Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?
  http://metadb.riken.jp/0002357I129SSvEvKmt2atm1ThrKmt2aMllt3tm2ThrMllt3TgLckcre1ThrKmt2aMllt3tm2ThrTgLckcre1ThrKmt2atm1ThrMllt3
• increased hemolymphoid system tumor incidence_Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?
  http://metadb.riken.jp/0010296I129SSvEvKmt2atm1ThrKmt2aMllt3tm2ThrMllt3TgLckcre1ThrKmt2aMllt3tm2ThrTgLckcre1ThrKmt2atm1ThrMllt3
• increased leukemia incidence_Lmo2<tm2(cre)Thr>/Lmo2<+>,Kmt2a<tm1Thr>/Kmt2a<+>,Mllt1<tm1Thr>/Mllt1<+>
  http://metadb.riken.jp/0002026I129SSvEvLmo2tm2creThrLmo2Kmt2atm1ThrKmt2aMllt1tm1ThrMllt1Kmt2atm1ThrMllt1Lmo2Mllt1tm1ThrLmo2tm2creThrKmt2a
• abnormal spleen red pulp morphology_Lmo2<tm2(cre)Thr>/Lmo2<+>,Kmt2a<tm1Thr>/Kmt2a<+>,Mllt1<tm1Thr>/Mllt1<+>
  http://metadb.riken.jp/0002356I129SSvEvLmo2tm2creThrLmo2Kmt2atm1ThrKmt2aMllt1tm1ThrMllt1Kmt2atm1ThrMllt1Lmo2Mllt1tm1ThrLmo2tm2creThrKmt2a
• increased T cell derived lymphoma incidence_Kmt2a<tm1Thr>/Kmt2a<+>,Mllt3<tm2Thr>/Mllt3<+>,Tg(Lck-cre)1Thr/?
  http://metadb.riken.jp/0002024I129SSvEvKmt2atm1ThrKmt2aMllt3tm2ThrMllt3TgLckcre1ThrKmt2aMllt3tm2ThrTgLckcre1ThrKmt2atm1ThrMllt3

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD09336
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD09336
• CD26046
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD26046