increased intestinal adenoma incidence_Apc<Min>/Apc<+>,Tcf7l2<tm2.2Mrc>/Tcf7l2<+>

http://metadb.riken.jp/0002404IC57BL6JApcMinApcTcf7l2tm22MrcTcf7l2Tcf7l2tm22MrcApcMinTcf7l2Apc

increased intestinal adenoma incidence_Apc<Min>/Apc<+>,Tcf7l2<tm2.2Mrc>/Tcf7l2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• transcription factor 7 like 2, T cell specific, HMG box
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202879

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<+>,Tcf7l2<tm2.2Mrc>/Tcf7l2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tcf7l2<tm2.2Mrc>|Apc<Min>|Tcf7l2<+>|Apc<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased intestinal adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002404

文献

http://purl.org/net/cito/citesAsAuthority

• Melinda L. Angus-Hill, et.al., T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21383188