abnormal T cell physiology_Vav1<tm1Tyb>/Vav1<tm1Tyb>

http://metadb.riken.jp/0002444I129S2SvPasVav1tm1TybVav1tm1TybVav1tm1Tyb

abnormal T cell physiology_Vav1<tm1Tyb>/Vav1<tm1Tyb>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vav 1 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98923

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vav1<tm1Tyb>/Vav1<tm1Tyb>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vav1<tm1Tyb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell physiology
  http://purl.obolibrary.org/obo/MP_0002444

文献

http://purl.org/net/cito/citesAsAuthority

• M. Turner, et.al., A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes., Immunity, 1997, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/9354466
• Keiko. Fujikawa, et.al., Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells., The Journal of experimental medicine, 2003, 198
  http://rdf.ncbi.nlm.nih.gov/pubmed/14623913