abnormal B cell physiology_Aicda<tm1Hon>/Aicda<tm1Hon>,Ighm<tm1.1(IGH-2)Cog>/Ighm<+>

http://metadb.riken.jp/0002459I129P2OlaHsdC57BL6CBAFVBNAicdatm1HonAicdatm1HonIghmtm11IGH2CogIghmIghmtm11IGH2CogAicdatm1HonIghm

abnormal B cell physiology_Aicda<tm1Hon>/Aicda<tm1Hon>,Ighm<tm1.1(IGH-2)Cog>/Ighm<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activation-induced cytidine deaminase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342279
• immunoglobulin heavy constant mu
  http://metadb.riken.jp/db/mgi_rdf/MGI:96448

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aicda<tm1Hon>/Aicda<tm1Hon>,Ighm<tm1.1(IGH-2)Cog>/Ighm<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ighm<tm1.1(IGH-2)Cog>|Aicda<tm1Hon>|Ighm<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal B cell physiology
  http://purl.obolibrary.org/obo/MP_0002459

文献

http://purl.org/net/cito/citesAsAuthority

• Sophie. Duchez, et.al., Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20133609