Sophie. Duchez, et.al., Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20133609

Sophie. Duchez, et.al., Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437126

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased B cell proliferation_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0005154I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• small Peyer's patches_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008135I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• increased B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0005014I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• increased pro-B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008186I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased IgA level_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0001807I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• abnormal B cell physiology_Aicda<tm1Hon>/Aicda<tm1Hon>,Ighm<tm1.1(IGH-2)Cog>/Ighm<+>
  http://metadb.riken.jp/0002459I129P2OlaHsdC57BL6CBAFVBNAicdatm1HonAicdatm1HonIghmtm11IGH2CogIghmIghmtm11IGH2CogAicdatm1HonIghm
• decreased marginal zone B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008182I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0005017I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased follicular B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008174I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased mature B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008211I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased B cell proliferation_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0005093I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased pre-B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008209I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased B-1 B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0004978I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• small lymph nodes_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0002217I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• abnormal B cell differentiation_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0002144I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• abnormal plasma cell differentiation_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008099I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased IgG3 level_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008498I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased IgG2a level_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008496I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased transitional stage B cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008190I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• increased mature B cell number_Blnk<tm1Pjln>/Blnk<tm1Pjln>
  http://metadb.riken.jp/0008210IBALBcBlnktm1PjlnBlnktm1PjlnBlnktm1Pjln
• increased plasma cell number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008097I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased IgG1 level_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008495I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased IgM level_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0001806I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased Peyer's patch number_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0008133I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog
• decreased IgG level_Ighm<tm1.1(IGH-2)Cog>/Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/0001805I129P2OlaHsdC57BL6FVBNIghmtm11IGH2CogIghmtm11IGH2CogIghmtm11IGH2Cog

class

http://purl.org/net/cito/citesAsAuthority

• Ighm<tm1.1(IGH-2)Cog>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437126