abnormal B cell physiology_Igh<tm1Ktom>/Igh<tm1Ktom>,Tc(HSA2)W23Ktom/0

http://metadb.riken.jp/0002459IC57BL6NCrljCBAJNCrljICRIghtm1KtomIghtm1KtomTcHSA2W23Ktom0Ightm1KtomTcHSA2W23Ktom

abnormal B cell physiology_Igh<tm1Ktom>/Igh<tm1Ktom>,Tc(HSA2)W23Ktom/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transchromosomal, human 2, line W23, Kazuma Tomizuka
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305484
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm1Ktom>/Igh<tm1Ktom>,Tc(HSA2)W23Ktom/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh<tm1Ktom>|Tc(HSA2)W23Ktom

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6NCrlj * CBA/JNCrlj * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal B cell physiology
  http://purl.obolibrary.org/obo/MP_0002459

文献

http://purl.org/net/cito/citesAsAuthority

• K. Tomizuka, et.al., Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies., Proceedings of the National Academy of Sciences of the United States of America, 2000, 97
  http://rdf.ncbi.nlm.nih.gov/pubmed/10639146