K. Tomizuka, et.al., Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies., Proceedings of the National Academy of Sciences of the United States of America, 2000, 97

http://rdf.ncbi.nlm.nih.gov/pubmed/10639146

K. Tomizuka, et.al., Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies., Proceedings of the National Academy of Sciences of the United States of America, 2000, 97

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tc(HSA14)SC20Ktom
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305481
• Igk<tm1Ktom>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305476
• Igh<tm1Ktom>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305473

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal B cell physiology_Igh<tm1Ktom>/Igh<tm1Ktom>,Igk<tm1Ktom>/Igk<tm1Ktom>,Tc(HSA14)SC20Ktom/0,Tc(HSA2)W23Ktom/0
  http://metadb.riken.jp/0002459IC57BL6NCrljCBAJNCrljICRIghtm1KtomIghtm1KtomIgktm1KtomIgktm1KtomTcHSA14SC20Ktom0TcHSA2W23Ktom0TcHSA14SC20KtomTcHSA2W23KtomIghtm1KtomIgktm1Ktom
• abnormal B cell physiology_Igh<tm1Ktom>/Igh<tm1Ktom>
  http://metadb.riken.jp/0002459IICRIghtm1KtomIghtm1KtomIghtm1Ktom
• abnormal B cell physiology_Igh<tm1Ktom>/Igh<tm1Ktom>,Tc(HSA2)W23Ktom/0
  http://metadb.riken.jp/0002459IC57BL6NCrljCBAJNCrljICRIghtm1KtomIghtm1KtomTcHSA2W23Ktom0Ightm1KtomTcHSA2W23Ktom

class

http://purl.org/net/cito/citesAsAuthority

• Tc(HSA14)SC20Ktom
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305481
• Igk<tm1Ktom>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305476
• Igh<tm1Ktom>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5305473