decreased immunoglobulin level_Aicda<tm1(cre)Njen>/Aicda<+>,Dicer1<tm1Bdh>/Dicer1<tm1Bdh>

http://metadb.riken.jp/0002460I129C57BL6Aicdatm1creNjenAicdaDicer1tm1BdhDicer1tm1BdhAicdaAicdatm1creNjenDicer1tm1Bdh

decreased immunoglobulin level_Aicda<tm1(cre)Njen>/Aicda<+>,Dicer1<tm1Bdh>/Dicer1<tm1Bdh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activation-induced cytidine deaminase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342279
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aicda<tm1(cre)Njen>/Aicda<+>,Dicer1<tm1Bdh>/Dicer1<tm1Bdh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Aicda<+>|Aicda<tm1(cre)Njen>|Dicer1<tm1Bdh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased immunoglobulin level
  http://purl.obolibrary.org/obo/MP_0002460

文献

http://purl.org/net/cito/citesAsAuthority

• Shengli. Xu, et.al., The RNase III enzyme Dicer is essential for germinal center B-cell formation., Blood, 2012, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/22117047