abnormal neutrophil physiology_Syk<tm1Tyb>/Syk<tm1.2Tara>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0002463I129P2OlaHsd129S2SvPasC57BL6Syktm1TybSyktm12TaraLyz2tm1creIfoLyz2Syktm1TybLyz2Syktm12TaraLyz2tm1creIfo

abnormal neutrophil physiology_Syk<tm1Tyb>/Syk<tm1.2Tara>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• spleen tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99515
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Syk<tm1Tyb>/Syk<tm1.2Tara>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Syk<tm1Tyb>|Lyz2<+>|Syk<tm1.2Tara>|Lyz2<tm1(cre)Ifo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neutrophil physiology
  http://purl.obolibrary.org/obo/MP_0002463

文献

http://purl.org/net/cito/citesAsAuthority

• Jessica A. Van Ziffle, et.al., Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection., Blood, 2009, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/19797524