Jessica A. Van Ziffle, et.al., Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection., Blood, 2009, 114

http://rdf.ncbi.nlm.nih.gov/pubmed/19797524

Jessica A. Van Ziffle, et.al., Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection., Blood, 2009, 114

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired granulocyte bactericidal activity_Itgam<tm1Myd>/Itgam<tm1Myd>,Syk<tm1Tyb>/Syk<tm1.2Tara>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0005074I129P2OlaHsd129S2SvPas129S4SvJaeC57BL6Itgamtm1MydItgamtm1MydSyktm1TybSyktm12TaraLyz2tm1creIfoLyz2Syktm1TybItgamtm1MydLyz2Lyz2tm1creIfoSyktm12Tara
• abnormal neutrophil physiology_Syk<tm1Tyb>/Syk<tm1Tyb>
  http://metadb.riken.jp/0002463I129S2SvPasSyktm1TybSyktm1TybSyktm1Tyb
• impaired granulocyte bactericidal activity_Syk<tm1Tyb>/Syk<tm1.2Tara>,Tg(S100A8-cre,-EGFP)1Ilw/0
  http://metadb.riken.jp/0005074I129P2OlaHsd129S2SvPasC3HC57BL6Syktm1TybSyktm12TaraTgS100A8creEGFP1Ilw0Syktm12TaraTgS100A8creEGFP1IlwSyktm1Tyb
• impaired neutrophil phagocytosis_Syk<tm1Tyb>/Syk<tm1Tyb>
  http://metadb.riken.jp/0002467I129S2SvPasSyktm1TybSyktm1TybSyktm1Tyb
• impaired granulocyte bactericidal activity_Syk<tm1Tyb>/Syk<tm1.2Tara>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0005074I129P2OlaHsd129S2SvPasC57BL6Syktm1TybSyktm12TaraLyz2tm1creIfoLyz2Syktm1TybLyz2Syktm12TaraLyz2tm1creIfo
• decreased tumor necrosis factor secretion_Syk<tm1Tyb>/Syk<tm1Tyb>
  http://metadb.riken.jp/0008561I129S2SvPasSyktm1TybSyktm1TybSyktm1Tyb
• impaired neutrophil phagocytosis_Itgam<tm1Myd>/Itgam<tm1Myd>
  http://metadb.riken.jp/0002467I129S4SvJaeItgamtm1MydItgamtm1MydItgamtm1Myd
• impaired granulocyte bactericidal activity_Syk<tm1Tyb>/Syk<tm1Tyb>
  http://metadb.riken.jp/0005074I129S2SvPasSyktm1TybSyktm1TybSyktm1Tyb
• abnormal neutrophil physiology_Syk<tm1Tyb>/Syk<tm1.2Tara>,Lyz2<tm1(cre)Ifo>/Lyz2<+>
  http://metadb.riken.jp/0002463I129P2OlaHsd129S2SvPasC57BL6Syktm1TybSyktm12TaraLyz2tm1creIfoLyz2Syktm1TybLyz2Syktm12TaraLyz2tm1creIfo