increased IgM level_Tbc1d10c<tm1.1Psou>/Tbc1d10c<tm1.2Psou>,Cd79a<tm1(cre)Reth>/Cd79a<+>

http://metadb.riken.jp/0002494I129S2SvPasBALBcC57BL6JTbc1d10ctm11PsouTbc1d10ctm12PsouCd79atm1creRethCd79aTbc1d10ctm11PsouCd79aCd79atm1creRethTbc1d10ctm12Psou

increased IgM level_Tbc1d10c<tm1.1Psou>/Tbc1d10c<tm1.2Psou>,Cd79a<tm1(cre)Reth>/Cd79a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774
• TBC1 domain family, member 10c
  http://metadb.riken.jp/db/mgi_rdf/MGI:1922072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tbc1d10c<tm1.1Psou>/Tbc1d10c<tm1.2Psou>,Cd79a<tm1(cre)Reth>/Cd79a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tbc1d10c<tm1.1Psou>|Cd79a<+>|Cd79a<tm1(cre)Reth>|Tbc1d10c<tm1.2Psou>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * BALB/c * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgM level
  http://purl.obolibrary.org/obo/MP_0002494

文献

http://purl.org/net/cito/citesAsAuthority

• Jean-Nicolas. Schickel, et.al., Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity., EMBO molecular medicine, 2012, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/23109291