increased IgA level_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm2Sjk>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0002495I129P2OlaHsd129S1Sv129X1SvJBak1tm1ThsnBak1tm1ThsnBaxtm1SjkBaxtm2SjkCd19tm1creCgnCd19Cd19Baxtm2SjkCd19tm1creCgnBaxtm1SjkBak1tm1Thsn

increased IgA level_Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm2Sjk>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• BCL2-antagonist/killer 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097161
• BCL2-associated X protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:99702
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bak1<tm1Thsn>/Bak1<tm1Thsn>,Bax<tm1Sjk>/Bax<tm2Sjk>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<+>|Bax<tm2Sjk>|Cd19<tm1(cre)Cgn>|Bax<tm1Sjk>|Bak1<tm1Thsn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgA level
  http://purl.obolibrary.org/obo/MP_0002495

文献

http://purl.org/net/cito/citesAsAuthority

• Osamu. Takeuchi, et.al., Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease., Proceedings of the National Academy of Sciences of the United States of America, 2005, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/16055554