increased IgA level_Tbk1<tm1Arte>/Tbk1<tm1Arte>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0002495I129SvEv129P2OlaHsdC57BL6Tbk1tm1ArteTbk1tm1ArteCd19tm1creCgnCd19Cd19tm1creCgnTbk1tm1ArteCd19

increased IgA level_Tbk1<tm1Arte>/Tbk1<tm1Arte>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• TANK-binding kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929658

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tbk1<tm1Arte>/Tbk1<tm1Arte>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<tm1(cre)Cgn>|Tbk1<tm1Arte>|Cd19<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/SvEv * 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgA level
  http://purl.obolibrary.org/obo/MP_0002495

文献

http://purl.org/net/cito/citesAsAuthority

• Jin. Jin, et.al., The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling., Nature immunology, 2012, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/23023393