increased IgE level_Itch<tm1.1Alta>/Itch<tm1.1Alta>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

http://metadb.riken.jp/0002497I129S1Sv129X1SvJC57BL6Itchtm11AltaItchtm11AltaFoxp3tm4YFPicreAyrFoxp3Foxp3Foxp3tm4YFPicreAyrItchtm11Alta

increased IgE level_Itch<tm1.1Alta>/Itch<tm1.1Alta>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box P3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891436
• itchy, E3 ubiquitin protein ligase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202301

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itch<tm1.1Alta>/Itch<tm1.1Alta>,Foxp3<tm4(YFP/icre)Ayr>/Foxp3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxp3<+>|Foxp3<tm4(YFP/icre)Ayr>|Itch<tm1.1Alta>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgE level
  http://purl.obolibrary.org/obo/MP_0002497

文献

http://purl.org/net/cito/citesAsAuthority

• Hyung-seung. Jin, et.al., Itch expression by Treg cells controls Th2 inflammatory responses., The Journal of clinical investigation, 2013, 123
  http://rdf.ncbi.nlm.nih.gov/pubmed/24135136