increased IgE level_Lat<tm1Mal>/Lat<tm1Mal>

http://metadb.riken.jp/0002497I129S2SvPasLattm1MalLattm1MalLattm1Mal

increased IgE level_Lat<tm1Mal>/Lat<tm1Mal>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• linker for activation of T cells
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342293

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lat<tm1Mal>/Lat<tm1Mal>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lat<tm1Mal>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgE level
  http://purl.obolibrary.org/obo/MP_0002497

文献

http://purl.org/net/cito/citesAsAuthority

• Enrique. Aguado, et.al., Induction of T helper type 2 immunity by a point mutation in the LAT adaptor., Science (New York, N.Y.), 2002, 296
  http://rdf.ncbi.nlm.nih.gov/pubmed/12065839
• Céline. Genton, et.al., The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity., Journal of immunology (Baltimore, Md. : 1950), 2006, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/16887989