Enrique. Aguado, et.al., Induction of T helper type 2 immunity by a point mutation in the LAT adaptor., Science (New York, N.Y.), 2002, 296

http://rdf.ncbi.nlm.nih.gov/pubmed/12065839

Enrique. Aguado, et.al., Induction of T helper type 2 immunity by a point mutation in the LAT adaptor., Science (New York, N.Y.), 2002, 296

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lat<tm1Mal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182312

class

http://purl.org/net/cito/citesAsAuthority

• Lat<tm1Mal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182312

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal immune system morphology_B2m<tm1Unc>/B2m<tm1Unc>,Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0000685I129P2OlaHsd129S2SvPasB2mtm1UncB2mtm1UncLattm1MalLattm1MalLattm1MalB2mtm1Unc
• enlarged spleen_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0000691I129S2SvPasLattm1MalLattm1MalLattm1Mal
• spleen hyperplasia_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0000693I129S2SvPasLattm1MalLattm1MalLattm1Mal
• enlarged lymph nodes_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0000702I129S2SvPasLattm1MalLattm1MalLattm1Mal
• absent CD8-positive, alpha-beta T cells_B2m<tm1Unc>/B2m<tm1Unc>,H2-Ab1<tm1Doi>/H2-Ab1<tm1Doi>,Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0000727I129P2OlaHsd129S2SvPasB2mtm1UncB2mtm1UncH2Ab1tm1DoiH2Ab1tm1DoiLattm1MalLattm1MalH2Ab1tm1DoiLattm1MalB2mtm1Unc
• absent CD8-positive, alpha-beta T cells_Cd3e<tm1Mal>/Cd3e<tm1Mal>,Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0000727I129S2SvPasC57BL6Cd3etm1MalCd3etm1MalLattm1MalLattm1MalLattm1MalCd3etm1Mal
他26件を見る
• absent CD8-positive, alpha-beta T cells_Cd3e<tm1Mal>/Cd3e<tm1Mal>
  http://metadb.riken.jp/0000727IC57BL6Cd3etm1MalCd3etm1MalCd3etm1Mal
• thymus hypoplasia_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0001823I129S2SvPasLattm1MalLattm1MalLattm1Mal
• arrested T cell differentiation_Cd3e<tm1Mal>/Cd3e<tm1Mal>,Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0001825I129S2SvPasC57BL6Cd3etm1MalCd3etm1MalLattm1MalLattm1MalLattm1MalCd3etm1Mal
• arrested T cell differentiation_Cd3e<tm1Mal>/Cd3e<tm1Mal>
  http://metadb.riken.jp/0001825IC57BL6Cd3etm1MalCd3etm1MalCd3etm1Mal
• increased IgE level_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0002497I129S2SvPasLattm1MalLattm1MalLattm1Mal
• chronic inflammation_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0002499I129S2SvPasLattm1MalLattm1MalLattm1Mal
• abnormal lymphocyte morphology_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0002619I129S2SvPasLattm1MalLattm1MalLattm1Mal
• abnormal immune system organ morphology_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0002722I129S2SvPasLattm1MalLattm1MalLattm1Mal
• abnormal immune serum protein physiology_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0002723I129S2SvPasLattm1MalLattm1MalLattm1Mal
• absent CD4-positive, alpha beta T cells_B2m<tm1Unc>/B2m<tm1Unc>,H2-Ab1<tm1Doi>/H2-Ab1<tm1Doi>,Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0003790I129P2OlaHsd129S2SvPasB2mtm1UncB2mtm1UncH2Ab1tm1DoiH2Ab1tm1DoiLattm1MalLattm1MalH2Ab1tm1DoiLattm1MalB2mtm1Unc
• absent CD4-positive, alpha beta T cells_Cd3e<tm1Mal>/Cd3e<tm1Mal>,Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0003790I129S2SvPasC57BL6Cd3etm1MalCd3etm1MalLattm1MalLattm1MalLattm1MalCd3etm1Mal
• absent CD4-positive, alpha beta T cells_Cd3e<tm1Mal>/Cd3e<tm1Mal>
  http://metadb.riken.jp/0003790IC57BL6Cd3etm1MalCd3etm1MalCd3etm1Mal
• abnormal T cell subpopulation ratio_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0003944I129S2SvPasLattm1MalLattm1MalLattm1Mal
• abnormal T cell selection_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0004917I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased eosinophil cell number_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0005011I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased B cell number_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0005014I129S2SvPasLattm1MalLattm1MalLattm1Mal
• decreased double-positive T cell number_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0005092I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased T cell proliferation_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0005348I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased memory T cell number_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0008049I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased CD4-positive, alpha beta T cell number_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0008074I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased T-helper 2 cell number_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0008090I129S2SvPasLattm1MalLattm1MalLattm1Mal
• abnormal B cell activation_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0008217I129S2SvPasLattm1MalLattm1MalLattm1Mal
• abnormal gamma-delta T cell differentiation_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0008356I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased IgG1 level_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0008499I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased interferon-gamma secretion_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0008566I129S2SvPasLattm1MalLattm1MalLattm1Mal
• increased interleukin-4 secretion_Lat<tm1Mal>/Lat<tm1Mal>
  http://metadb.riken.jp/0008699I129S2SvPasLattm1MalLattm1MalLattm1Mal