increased hematocrit_Egln1<tm2Fong>/Egln1<tm2Fong>,Egln2<tm2Fong>/Egln2<tm2Fong>,Egln3<tm2Fong>/Egln3<tm2Fong>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

http://metadb.riken.jp/0002608I129S6SvEvTacC57BL6NCrCD1Egln1tm2FongEgln1tm2FongEgln2tm2FongEgln2tm2FongEgln3tm2FongEgln3tm2FongTgSp7tTAtetOEGFPcre1Amc0Egln2tm2FongEgln1tm2FongEgln3tm2FongTgSp7tTAtetOEGFPcre1Amc

increased hematocrit_Egln1<tm2Fong>/Egln1<tm2Fong>,Egln2<tm2Fong>/Egln2<tm2Fong>,Egln3<tm2Fong>/Egln3<tm2Fong>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• egl-9 family hypoxia-inducible factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932287
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3689349
• egl-9 family hypoxia-inducible factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932286
• egl-9 family hypoxia-inducible factor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1932288

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Egln1<tm2Fong>/Egln1<tm2Fong>,Egln2<tm2Fong>/Egln2<tm2Fong>,Egln3<tm2Fong>/Egln3<tm2Fong>,Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Egln2<tm2Fong>|Egln1<tm2Fong>|Egln3<tm2Fong>|Tg(Sp7-tTA,tetO-EGFP/cre)1Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6NCr * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hematocrit
  http://purl.obolibrary.org/obo/MP_0002608

文献

http://purl.org/net/cito/citesAsAuthority

• Erinn B. Rankin, et.al., The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO., Cell, 2012, 149
  http://rdf.ncbi.nlm.nih.gov/pubmed/22464323