persistent truncus arteriosis_Braf<tm1Wds>/Braf<tm1Wds>,Raf1<tm2Bacc>/Raf1<tm2Bacc>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0002633I129P2OlaHsdC57BL6JCBAJBraftm1WdsBraftm1WdsRaf1tm2BaccRaf1tm2BaccTgWnt1cre11Rth0TgWnt1cre11RthRaf1tm2BaccBraftm1Wds

persistent truncus arteriosis_Braf<tm1Wds>/Braf<tm1Wds>,Raf1<tm2Bacc>/Raf1<tm2Bacc>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280
• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190
• v-raf-leukemia viral oncogene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97847

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm1Wds>/Braf<tm1Wds>,Raf1<tm2Bacc>/Raf1<tm2Bacc>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Wnt1-cre)11Rth|Raf1<tm2Bacc>|Braf<tm1Wds>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• persistent truncus arteriosis
  http://purl.obolibrary.org/obo/MP_0002633

文献

http://purl.org/net/cito/citesAsAuthority

• Jason. Newbern, et.al., Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18952847