persistent truncus arteriosis_Map2k1<tm1Chrn>/Map2k1<tm1Chrn>,Map2k2<tm1Chrn>/Map2k2<tm1Chrn>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0002633I129SvC57BL6JCBAJSJLMap2k1tm1ChrnMap2k1tm1ChrnMap2k2tm1ChrnMap2k2tm1ChrnTgWnt1cre11Rth0Map2k2tm1ChrnTgWnt1cre11RthMap2k1tm1Chrn

persistent truncus arteriosis_Map2k1<tm1Chrn>/Map2k1<tm1Chrn>,Map2k2<tm1Chrn>/Map2k2<tm1Chrn>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitogen-activated protein kinase kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346867
• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280
• mitogen-activated protein kinase kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346866

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Map2k1<tm1Chrn>/Map2k1<tm1Chrn>,Map2k2<tm1Chrn>/Map2k2<tm1Chrn>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Map2k2<tm1Chrn>|Tg(Wnt1-cre)11Rth|Map2k1<tm1Chrn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * CBA/J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• persistent truncus arteriosis
  http://purl.obolibrary.org/obo/MP_0002633

文献

http://purl.org/net/cito/citesAsAuthority

• Jason. Newbern, et.al., Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18952847