decreased circulating glucagon level_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0

http://metadb.riken.jp/0002696IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich

decreased circulating glucagon level_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 23, Pedro Luis Herrera
  http://metadb.riken.jp/db/mgi_rdf/MGI:4431238

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-cre)23Herr|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating glucagon level
  http://purl.obolibrary.org/obo/MP_0002696

文献

http://purl.org/net/cito/citesAsAuthority

• Maria Sara. Remedi, et.al., Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitus., Cell metabolism, 2009, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/19187772