Maria Sara. Remedi, et.al., Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitus., Cell metabolism, 2009, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/19187772

Maria Sara. Remedi, et.al., Secondary consequences of beta cell inexcitability: identification and prevention in a murine model of K(ATP)-induced neonatal diabetes mellitus., Cell metabolism, 2009, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3838361

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3838361

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal circulating glucose level_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0000188IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• hyperglycemia_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0001559IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• abnormal pancreas morphology_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0001944IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• abnormal circulating glucagon level_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0002695IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• decreased circulating glucagon level_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0002696IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• increased circulating glucagon level_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0002712IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
他11件を見る
• decreased circulating insulin level_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0002727IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• decreased insulin secretion_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0003059IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• decreased pancreatic beta cell number_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0003339IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• abnormal pancreatic beta cell physiology_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0003562IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• abnormal pancreatic islet morphology_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0005215IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• abnormal pancreatic alpha cell morphology_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0005216IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• slow postnatal weight gain_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0008489IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• decreased pancreas weight_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0009109IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• decreased pancreatic islet number_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0009168IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• small pancreatic islets_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0009172IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich
• decreased pancreatic alpha cell number_Gt(ROSA)26Sor<tm1(CAG-Kcnj11*,-GFP)Nich>/Gt(ROSA)26Sor<+>,Tg(Ins2-cre)23Herr/0
  http://metadb.riken.jp/0009177IC57BL6CBAJGtROSA26Sortm1CAGKcnj11GFPNichGtROSA26SorTgIns2cre23Herr0TgIns2cre23HerrGtROSA26SorGtROSA26Sortm1CAGKcnj11GFPNich