abnormal renal tubule morphology_Ahi1<tm1Jgg>/Ahi1<+>,Lrp6<Gt(Ex187)Byg>/Lrp6<+>

http://metadb.riken.jp/0002703I129P2OlaHsd129S1Sv129X1SvJAhi1tm1JggAhi1Lrp6GtEx187BygLrp6Lrp6Ahi1tm1JggAhi1Lrp6GtEx187Byg

abnormal renal tubule morphology_Ahi1<tm1Jgg>/Ahi1<+>,Lrp6<Gt(Ex187)Byg>/Lrp6<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Abelson helper integration site 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:87971
• low density lipoprotein receptor-related protein 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1298218

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ahi1<tm1Jgg>/Ahi1<+>,Lrp6<Gt(Ex187)Byg>/Lrp6<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lrp6<+>|Ahi1<tm1Jgg>|Ahi1<+>|Lrp6<Gt(Ex187)Byg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal renal tubule morphology
  http://purl.obolibrary.org/obo/MP_0002703

文献

http://purl.org/net/cito/citesAsAuthority

• Madeline A. Lancaster, et.al., Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy., Nature medicine, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19718039