decreased circulating insulin level_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0002727I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam

decreased circulating insulin level_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• met proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:96969
• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Met<tm1Sst>|Tg(Pdx1-cre)89.1Dam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating insulin level
  http://purl.obolibrary.org/obo/MP_0002727

文献

http://purl.org/net/cito/citesAsAuthority

• Cem. Demirci, et.al., Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus., Diabetes, 2012, 61
  http://rdf.ncbi.nlm.nih.gov/pubmed/22427375