Cem. Demirci, et.al., Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus., Diabetes, 2012, 61

http://rdf.ncbi.nlm.nih.gov/pubmed/22427375

Cem. Demirci, et.al., Loss of HGF/c-Met signaling in pancreatic β-cells leads to incomplete maternal β-cell adaptation and gestational diabetes mellitus., Diabetes, 2012, 61

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased pancreatic beta cell mass_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009114I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam
• abnormal pancreatic beta cell physiology_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003562I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam
• decreased circulating insulin level_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0002727I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam
• abnormal pancreatic islet morphology_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005215I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam
• impaired glucose tolerance_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005293I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam
• decreased pancreatic beta cell proliferation_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0011820I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam
• increased circulating glucose level_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005559I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam
• decreased insulin secretion_Met<tm1Sst>/Met<tm1Sst>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003059I129P2OlaHsdC57BL6CBAMettm1SstMettm1SstTgPdx1cre891Dam0Mettm1SstTgPdx1cre891Dam