glomerulonephritis_Lyn<tm1Sor>/Lyn<tm1Sor>

http://metadb.riken.jp/0002743I129S4SvJaeSorLyntm1SorLyntm1SorLyntm1Sor

glomerulonephritis_Lyn<tm1Sor>/Lyn<tm1Sor>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• LYN proto-oncogene, Src family tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96892

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lyn<tm1Sor>/Lyn<tm1Sor>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyn<tm1Sor>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• glomerulonephritis
  http://purl.obolibrary.org/obo/MP_0002743

文献

http://purl.org/net/cito/citesAsAuthority

• Rina. Barouch-Bentov, et.al., A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function., Molecular cell, 2009, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/19150426
• Chrystelle. Lamagna, et.al., Hyperactivated MyD88 signaling in dendritic cells, through specific deletion of Lyn kinase, causes severe autoimmunity and inflammation., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23940344