increased circulating testosterone level_Por<tm3Ding>/Por<tm3Ding>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0002781IC57BL6DBAPortm3DingPortm3DingTgAlbcre21Mgn0Portm3DingTgAlbcre21Mgn

increased circulating testosterone level_Por<tm3Ding>/Por<tm3Ding>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• P450 (cytochrome) oxidoreductase
  http://metadb.riken.jp/db/mgi_rdf/MGI:97744
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Por<tm3Ding>/Por<tm3Ding>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Por<tm3Ding>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating testosterone level
  http://purl.obolibrary.org/obo/MP_0002781

文献

http://purl.org/net/cito/citesAsAuthority

• Yuan. Wei, et.al., Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a resultant mouse model with global suppression of P450 reductase expression in extrahepatic tissues., The Journal of pharmacology and experimental therapeutics, 2010, 334
  http://rdf.ncbi.nlm.nih.gov/pubmed/20375200