Yuan. Wei, et.al., Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a resultant mouse model with global suppression of P450 reductase expression in extrahepatic tissues., The Journal of pharmacology and experimental therapeutics, 2010, 334

http://rdf.ncbi.nlm.nih.gov/pubmed/20375200

Yuan. Wei, et.al., Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a resultant mouse model with global suppression of P450 reductase expression in extrahepatic tissues., The Journal of pharmacology and experimental therapeutics, 2010, 334

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Por<tm3Ding>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4457492

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased kidney weight_Por<tm3Ding>/Por<tm3Ding>
  http://metadb.riken.jp/0003918C57BL6Portm3DingPortm3DingPortm3DingPortm3Ding
• increased circulating testosterone level_Por<tm3Ding>/Por<tm3Ding>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002781IC57BL6DBAPortm3DingPortm3DingTgAlbcre21Mgn0Portm3DingTgAlbcre21Mgn
• enhanced behavioral response to anesthetic_Por<tm3Ding>/Por<tm3Ding>
  http://metadb.riken.jp/0009779C57BL6Portm3DingPortm3DingPortm3DingPortm3Ding
• decreased lung weight_Por<tm3Ding>/Por<tm3Ding>
  http://metadb.riken.jp/0005631C57BL6Portm3DingPortm3DingPortm3DingPortm3Ding
• female infertility_Por<tm3Ding>/Por<tm3Ding>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001926IC57BL6DBAPortm3DingPortm3DingTgAlbcre21Mgn0Portm3DingTgAlbcre21Mgn
• increased circulating progesterone level_Por<tm3Ding>/Por<tm3Ding>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005186IC57BL6DBAPortm3DingPortm3DingTgAlbcre21Mgn0Portm3DingTgAlbcre21Mgn
• female infertility_Por<tm3Ding>/Por<tm3Ding>
  http://metadb.riken.jp/0001926C57BL6Portm3DingPortm3DingPortm3DingPortm3Ding
• abnormal enzyme/coenzyme activity_Por<tm3Ding>/Por<tm3Ding>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005584IC57BL6DBAPortm3DingPortm3DingTgAlbcre21Mgn0Portm3DingTgAlbcre21Mgn
• preweaning lethality, incomplete penetrance_Por<tm3Ding>/Por<tm3Ding>
  http://metadb.riken.jp/0011110IC57BL6DBAPortm3DingPortm3DingPortm3Ding
• decreased heart weight_Por<tm3Ding>/Por<tm3Ding>
  http://metadb.riken.jp/0002834C57BL6Portm3DingPortm3DingPortm3DingPortm3Ding
• decreased body weight_Por<tm3Ding>/Por<tm3Ding>
  http://metadb.riken.jp/0001262C57BL6Portm3DingPortm3DingPortm3DingPortm3Ding
• decreased circulating cholesterol level_Por<tm3Ding>/Por<tm3Ding>
  http://metadb.riken.jp/0005179C57BL6Portm3DingPortm3DingPortm3DingPortm3Ding

class

http://purl.org/net/cito/citesAsAuthority

• Por<tm3Ding>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4457492

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD15689
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15689