decreased heart weight_Pik3ca<tm1.1Rzl>/Pik3ca<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

http://metadb.riken.jp/0002834I129S4SvJaeSorC57BL6FVBNPik3catm11RzlPik3catm11RzlA1cfTgMyh6creEsr11Jmk0A1cfTgMyh6creEsr11JmkPik3catm11Rzl

decreased heart weight_Pik3ca<tm1.1Rzl>/Pik3ca<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1206581
• APOBEC1 complementation factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917115

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3ca<tm1.1Rzl>/Pik3ca<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• A1cf<Tg(Myh6-cre/Esr1*)1Jmk>|Pik3ca<tm1.1Rzl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased heart weight
  http://purl.obolibrary.org/obo/MP_0002834

文献

http://purl.org/net/cito/citesAsAuthority

• Zhongju. Lu, et.al., Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction., Circulation, 2009, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/19597047