Zhongju. Lu, et.al., Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction., Circulation, 2009, 120

http://rdf.ncbi.nlm.nih.gov/pubmed/19597047

Zhongju. Lu, et.al., Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction., Circulation, 2009, 120

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pik3cb<tm1.1Rzl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4845857
• Pik3ca<tm1.1Rzl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4845856

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber physiology_Pik3ca<tm1.1Rzl>/Pik3ca<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0004215I129S4SvJaeSorC57BL6FVBNPik3catm11RzlPik3catm11RzlA1cfTgMyh6creEsr11Jmk0A1cfTgMyh6creEsr11JmkPik3catm11Rzl
• thick ventricular wall_Pik3ca<tm1.1Rzl>/Pik3ca<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002953I129S4SvJaeSorC57BL6FVBNPik3catm11RzlPik3catm11RzlA1cfTgMyh6creEsr11Jmk0A1cfTgMyh6creEsr11JmkPik3catm11Rzl
• decreased cardiac muscle contractility_Pik3ca<tm1.1Rzl>/Pik3ca<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0005140I129S4SvJaeSorC57BL6FVBNPik3catm11RzlPik3catm11RzlA1cfTgMyh6creEsr11Jmk0A1cfTgMyh6creEsr11JmkPik3catm11Rzl
• decreased heart weight_Pik3cb<tm1.1Rzl>/Pik3cb<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002834I129S4SvJaeSorC57BL6FVBNPik3cbtm11RzlPik3cbtm11RzlA1cfTgMyh6creEsr11Jmk0A1cfTgMyh6creEsr11JmkPik3cbtm11Rzl
• decreased heart weight_Pik3ca<tm1.1Rzl>/Pik3ca<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0002834I129S4SvJaeSorC57BL6FVBNPik3catm11RzlPik3catm11RzlA1cfTgMyh6creEsr11Jmk0A1cfTgMyh6creEsr11JmkPik3catm11Rzl
• increased heart left ventricle size_Pik3ca<tm1.1Rzl>/Pik3ca<tm1.1Rzl>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0010579I129S4SvJaeSorC57BL6FVBNPik3catm11RzlPik3catm11RzlA1cfTgMyh6creEsr11Jmk0A1cfTgMyh6creEsr11JmkPik3catm11Rzl

class

http://purl.org/net/cito/citesAsAuthority

• Pik3cb<tm1.1Rzl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4845857
• Pik3ca<tm1.1Rzl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4845856