decreased systemic arterial blood pressure_Gna12<tm1Citb>/Gna12<tm1Citb>,Gna13<tm2.1Soff>/Gna13<tm2.1Soff>,X/Tg(Myh11-cre/ERT2)1Soff

http://metadb.riken.jp/0002843I129S1SvFVBNGna12tm1CitbGna12tm1CitbGna13tm21SoffGna13tm21SoffXTgMyh11creERT21SoffGna13tm21SoffTgMyh11creERT21SoffGna12tm1Citb

decreased systemic arterial blood pressure_Gna12<tm1Citb>/Gna12<tm1Citb>,Gna13<tm2.1Soff>/Gna13<tm2.1Soff>,X/Tg(Myh11-cre/ERT2)1Soff

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• guanine nucleotide binding protein, alpha 12
  http://metadb.riken.jp/db/mgi_rdf/MGI:95767
• guanine nucleotide binding protein, alpha 13
  http://metadb.riken.jp/db/mgi_rdf/MGI:95768
• transgene insertion 1, Stefan Offermanns
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819268

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gna12<tm1Citb>/Gna12<tm1Citb>,Gna13<tm2.1Soff>/Gna13<tm2.1Soff>,X/Tg(Myh11-cre/ERT2)1Soff

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gna13<tm2.1Soff>|Tg(Myh11-cre/ERT2)1Soff|Gna12<tm1Citb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased systemic arterial blood pressure
  http://purl.obolibrary.org/obo/MP_0002843

文献

http://purl.org/net/cito/citesAsAuthority

• Angela. Wirth, et.al., G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension., Nature medicine, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18084302