Angela. Wirth, et.al., G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension., Nature medicine, 2008, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/18084302

Angela. Wirth, et.al., G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension., Nature medicine, 2008, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh11-cre/ERT2)1Soff
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819270
• Arhgef12<tm1Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819185

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh11-cre/ERT2)1Soff
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819270
• Arhgef12<tm1Soff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819185

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased systemic arterial blood pressure_Arhgef12<tm1Soff>/Arhgef12<tm1Soff>
  http://metadb.riken.jp/0002843NSArhgef12tm1SoffArhgef12tm1SoffArhgef12tm1Soff
• decreased vasoconstriction_Arhgef12<tm1Soff>/Arhgef12<tm1Soff>
  http://metadb.riken.jp/0003026NSArhgef12tm1SoffArhgef12tm1SoffArhgef12tm1Soff
• decreased mean systemic arterial blood pressure_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,X/Tg(Myh11-cre/ERT2)1Soff
  http://metadb.riken.jp/0004876I129P2OlaHsd129S7SvEvBrdFVBNGna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffXTgMyh11creERT21SoffGnaqtm2SoffTgMyh11creERT21SoffGna11tm1Soff
• decreased systemic arterial blood pressure_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,X/Tg(Myh11-cre/ERT2)1Soff
  http://metadb.riken.jp/0002843I129P2OlaHsd129S7SvEvBrdFVBNGna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffXTgMyh11creERT21SoffGnaqtm2SoffTgMyh11creERT21SoffGna11tm1Soff
• decreased vasoconstriction_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,X/Tg(Myh11-cre/ERT2)1Soff
  http://metadb.riken.jp/0003026I129P2OlaHsd129S7SvEvBrdFVBNGna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffXTgMyh11creERT21SoffGnaqtm2SoffTgMyh11creERT21SoffGna11tm1Soff
• decreased vasoconstriction_Gna12<tm1Citb>/Gna12<tm1Citb>,Gna13<tm2.1Soff>/Gna13<tm2.1Soff>,X/Tg(Myh11-cre/ERT2)1Soff
  http://metadb.riken.jp/0003026I129S1SvFVBNGna12tm1CitbGna12tm1CitbGna13tm21SoffGna13tm21SoffXTgMyh11creERT21SoffGna13tm21SoffTgMyh11creERT21SoffGna12tm1Citb
• decreased systemic arterial blood pressure_Gna12<tm1Citb>/Gna12<tm1Citb>,Gna13<tm2.1Soff>/Gna13<tm2.1Soff>,X/Tg(Myh11-cre/ERT2)1Soff
  http://metadb.riken.jp/0002843I129S1SvFVBNGna12tm1CitbGna12tm1CitbGna13tm21SoffGna13tm21SoffXTgMyh11creERT21SoffGna13tm21SoffTgMyh11creERT21SoffGna12tm1Citb
• decreased systemic arterial blood pressure_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,X/Tg(Myh11-cre/ERT2)1Soff
  http://metadb.riken.jp/0002843I129P2OlaHsd129S7SvEvBrdFVBNGna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffXTgMyh11creERT21SoffGna11tm1SoffTgMyh11creERT21SoffGnaqtm2Soff