albuminuria_Gt(ROSA)26Sor<tm1.1(Ubc-ROCK1*)Dnsh>/Gt(ROSA)26Sor<+>,Tg(NPHS2-icre/ERT2)1Dnsh/0

http://metadb.riken.jp/0002871IC57BL6GtROSA26Sortm11UbcROCK1DnshGtROSA26SorTgNPHS2icreERT21Dnsh0TgNPHS2icreERT21DnshGtROSA26Sortm11UbcROCK1DnshGtROSA26Sor

albuminuria_Gt(ROSA)26Sor<tm1.1(Ubc-ROCK1*)Dnsh>/Gt(ROSA)26Sor<+>,Tg(NPHS2-icre/ERT2)1Dnsh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Farhad R Danesh
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819591

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1.1(Ubc-ROCK1*)Dnsh>/Gt(ROSA)26Sor<+>,Tg(NPHS2-icre/ERT2)1Dnsh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(NPHS2-icre/ERT2)1Dnsh|Gt(ROSA)26Sor<tm1.1(Ubc-ROCK1*)Dnsh>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• albuminuria
  http://purl.obolibrary.org/obo/MP_0002871

文献

http://purl.org/net/cito/citesAsAuthority

• Wenjian. Wang, et.al., Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells., Cell metabolism, 2012, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/22326220