abnormal joint morphology_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0

http://metadb.riken.jp/0002932I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm11YyPtch1tm11YyPtch1tm1YyTgCol2a1cre1BhrCtnnb1tm1Yy

abnormal joint morphology_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• patched 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:105373
• transgene insertion 1, Richard R Behringer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176069

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctnnb1<tm1.1Yy>|Ptch1<tm1.1Yy>|Ptch1<tm1Yy>|Tg(Col2a1-cre)1Bhr|Ctnnb1<tm1Yy>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal joint morphology
  http://purl.obolibrary.org/obo/MP_0002932

文献

http://purl.org/net/cito/citesAsAuthority

• Kingston Kinglun. Mak, et.al., Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation., Development (Cambridge, England), 2006, 133
  http://rdf.ncbi.nlm.nih.gov/pubmed/16936073