Kingston Kinglun. Mak, et.al., Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation., Development (Cambridge, England), 2006, 133

http://rdf.ncbi.nlm.nih.gov/pubmed/16936073

Kingston Kinglun. Mak, et.al., Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation., Development (Cambridge, England), 2006, 133

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ptch1<tm1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687452
• Ptch1<tm1.1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687453

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal joint morphology_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0002932I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm11YyPtch1tm11YyPtch1tm1YyTgCol2a1cre1BhrCtnnb1tm1Yy
• abnormal chondrocyte morphology_Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000166IC57BL6SJLPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0TgCol2a1cre1BhrPtch1tm1YyPtch1tm11Yy
• decreased bone mineralization_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0020137I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm11YyPtch1tm11YyPtch1tm1YyTgCol2a1cre1BhrCtnnb1tm1Yy
• abnormal long bone hypertrophic chondrocyte zone_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000165I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm11YyPtch1tm11YyPtch1tm1YyTgCol2a1cre1BhrCtnnb1tm1Yy
• abnormal cartilage morphology_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000163I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm11YyPtch1tm11YyPtch1tm1YyTgCol2a1cre1BhrCtnnb1tm1Yy
• failure of bone ossification_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0008274I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm1YyTgCol2a1cre1BhrCtnnb1tm11Yy
• fused synovial joints_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003190I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm11YyPtch1tm11YyPtch1tm1YyTgCol2a1cre1BhrCtnnb1tm1Yy
• abnormal bone ossification_Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0008271IC57BL6SJLPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0TgCol2a1cre1BhrPtch1tm1YyPtch1tm11Yy
• prenatal lethality, incomplete penetrance_Ptch1<tm1Yy>/Ptch1<tm1Yy>
  http://metadb.riken.jp/0011101NSPtch1tm1YyPtch1tm1YyPtch1tm1Yy
• decreased bone mineralization_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0020137I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm1YyTgCol2a1cre1BhrCtnnb1tm11Yy
• delayed endochondral bone ossification_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003419I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm11YyPtch1tm11YyPtch1tm1YyTgCol2a1cre1BhrCtnnb1tm1Yy
• fused synovial joints_Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0003190IC57BL6SJLPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0TgCol2a1cre1BhrPtch1tm1YyPtch1tm11Yy
• abnormal cranium morphology_Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000438IC57BL6SJLPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0TgCol2a1cre1BhrPtch1tm1YyPtch1tm11Yy
• abnormal perichondrium morphology_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0006322I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm1YyTgCol2a1cre1BhrCtnnb1tm11Yy
• abnormal long bone hypertrophic chondrocyte zone_Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000165IC57BL6SJLPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0TgCol2a1cre1BhrPtch1tm1YyPtch1tm11Yy
• decreased length of long bones_Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0004686IC57BL6SJLPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0TgCol2a1cre1BhrPtch1tm1YyPtch1tm11Yy
• abnormal osteoblast physiology_Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0005006IC57BL6SJLPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0TgCol2a1cre1BhrPtch1tm1YyPtch1tm11Yy
• abnormal chondrocyte morphology_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000166I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm1YyTgCol2a1cre1BhrCtnnb1tm11Yy
• abnormal bone mineralization_Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0002896IC57BL6SJLPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0TgCol2a1cre1BhrPtch1tm1YyPtch1tm11Yy
• decreased osteoblast cell number_Ctnnb1<tm1Yy>/Ctnnb1<tm1.1Yy>,Ptch1<tm1Yy>/Ptch1<tm1.1Yy>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0004989I129S6SvEvTacC57BL6SJLCtnnb1tm1YyCtnnb1tm11YyPtch1tm1YyPtch1tm11YyTgCol2a1cre1Bhr0Ctnnb1tm11YyPtch1tm11YyPtch1tm1YyTgCol2a1cre1BhrCtnnb1tm1Yy

class

http://purl.org/net/cito/citesAsAuthority

• Ptch1<tm1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687452
• Ptch1<tm1.1Yy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687453