increased circulating alanine transaminase level_Hmgcr<tm2Ishi>/Hmgcr<tm2Ishi>,Tg(Alb1-cre)1Dlr/0

http://metadb.riken.jp/0002941I129S7SvEvBrdC57BL6JHmgcrtm2IshiHmgcrtm2IshiTgAlb1cre1Dlr0TgAlb1cre1DlrHmgcrtm2Ishi

increased circulating alanine transaminase level_Hmgcr<tm2Ishi>/Hmgcr<tm2Ishi>,Tg(Alb1-cre)1Dlr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96159
• transgene insertion 1, Derek LeRoith
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176944

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hmgcr<tm2Ishi>/Hmgcr<tm2Ishi>,Tg(Alb1-cre)1Dlr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb1-cre)1Dlr|Hmgcr<tm2Ishi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating alanine transaminase level
  http://purl.obolibrary.org/obo/MP_0002941

文献

http://purl.org/net/cito/citesAsAuthority

• Shuichi. Nagashima, et.al., Liver-specific deletion of 3-hydroxy-3-methylglutaryl coenzyme A reductase causes hepatic steatosis and death., Arteriosclerosis, thrombosis, and vascular biology, 2012, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22701022