decreased circulating alanine transaminase level_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Tg(Cebpb-tTA)5Bjd/0

http://metadb.riken.jp/0002942I129S4SvJaeC57BL6NMRICol1a1tm3tetOFosl1DsRedWagCol1a1TgCebpbtTA5Bjd0TgCebpbtTA5BjdCol1a1tm3tetOFosl1DsRedWagCol1a1

decreased circulating alanine transaminase level_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Tg(Cebpb-tTA)5Bjd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• transgene insertion 5, Hermann Bujard
  http://metadb.riken.jp/db/mgi_rdf/MGI:3056822

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Tg(Cebpb-tTA)5Bjd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cebpb-tTA)5Bjd|Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>|Col1a1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * NMRI

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating alanine transaminase level
  http://purl.obolibrary.org/obo/MP_0002942

文献

http://purl.org/net/cito/citesAsAuthority

• Sebastian C. Hasenfuss, et.al., Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers., Cell metabolism, 2014, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/24411941
• Sebastian C. Hasenfuss, et.al., Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism., Hepatology (Baltimore, Md.), 2014, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/23703832