Sebastian C. Hasenfuss, et.al., Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism., Hepatology (Baltimore, Md.), 2014, 59

http://rdf.ncbi.nlm.nih.gov/pubmed/23703832

Sebastian C. Hasenfuss, et.al., Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism., Hepatology (Baltimore, Md.), 2014, 59

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5585716

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal skeleton morphology_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005508I129S4SvJaeC57BL6Col1a1tm3tetOFosl1DsRedWagCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm3tetOFosl1DsRedWag
• lethargy_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005202I129S4SvJaeC57BL6Col1a1tm3tetOFosl1DsRedWagCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm3tetOFosl1DsRedWag
• enlarged spleen_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0000691I129S4SvJaeC57BL6Col1a1tm3tetOFosl1DsRedWagCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm3tetOFosl1DsRedWag
• decreased circulating alanine transaminase level_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Tg(Cebpb-tTA)5Bjd/0
  http://metadb.riken.jp/0002942I129S4SvJaeC57BL6NMRICol1a1tm3tetOFosl1DsRedWagCol1a1TgCebpbtTA5Bjd0TgCebpbtTA5BjdCol1a1tm3tetOFosl1DsRedWagCol1a1
• increased bile salt level_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Tg(Cebpb-tTA)5Bjd/0
  http://metadb.riken.jp/0004789I129S4SvJaeC57BL6NMRICol1a1tm3tetOFosl1DsRedWagCol1a1TgCebpbtTA5Bjd0TgCebpbtTA5BjdCol1a1tm3tetOFosl1DsRedWagCol1a1
• weight loss_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001263I129S4SvJaeC57BL6Col1a1tm3tetOFosl1DsRedWagCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm3tetOFosl1DsRedWag
• decreased circulating cholesterol level_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Tg(Cebpb-tTA)5Bjd/0
  http://metadb.riken.jp/0005179I129S4SvJaeC57BL6NMRICol1a1tm3tetOFosl1DsRedWagCol1a1TgCebpbtTA5Bjd0TgCebpbtTA5BjdCol1a1tm3tetOFosl1DsRedWagCol1a1
• liver fibrosis_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003333I129S4SvJaeC57BL6Col1a1tm3tetOFosl1DsRedWagCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm3tetOFosl1DsRedWag
• ascites_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005324I129S4SvJaeC57BL6Col1a1tm3tetOFosl1DsRedWagCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorCol1a1tm3tetOFosl1DsRedWag
• decreased susceptibility to injury_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Tg(Cebpb-tTA)5Bjd/0
  http://metadb.riken.jp/0005166I129S4SvJaeC57BL6NMRICol1a1tm3tetOFosl1DsRedWagCol1a1TgCebpbtTA5Bjd0TgCebpbtTA5BjdCol1a1tm3tetOFosl1DsRedWagCol1a1
• increased liver weight_Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>/Col1a1<+>,Tg(Cebpb-tTA)5Bjd/0
  http://metadb.riken.jp/0002981I129S4SvJaeC57BL6NMRICol1a1tm3tetOFosl1DsRedWagCol1a1TgCebpbtTA5Bjd0TgCebpbtTA5BjdCol1a1tm3tetOFosl1DsRedWagCol1a1

class

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm3(tetO-Fosl1,-DsRed)Wag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5585716