abnormal inhibitory postsynaptic currents_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>,Tg(Pomc1-hrGFP)1Lowl/0

http://metadb.riken.jp/0002945I129S6SvEvTacFVBNLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1TgPomc1hrGFP1Lowl0Leprtm11ChuaSlc32a1Slc32a1tm2creLowlTgPomc1hrGFP1Lowl

abnormal inhibitory postsynaptic currents_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>,Tg(Pomc1-hrGFP)1Lowl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• solute carrier family 32 (GABA vesicular transporter), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1194488
• transgene insertion 1, Bradford B Lowell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3709186
• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>,Tg(Pomc1-hrGFP)1Lowl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lepr<tm1.1Chua>|Slc32a1<+>|Slc32a1<tm2(cre)Lowl>|Tg(Pomc1-hrGFP)1Lowl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal inhibitory postsynaptic currents
  http://purl.obolibrary.org/obo/MP_0002945

文献

http://purl.org/net/cito/citesAsAuthority

• Linh. Vong, et.al., Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons., Neuron, 2011, 71
  http://rdf.ncbi.nlm.nih.gov/pubmed/21745644