Linh. Vong, et.al., Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons., Neuron, 2011, 71

http://rdf.ncbi.nlm.nih.gov/pubmed/21745644

Linh. Vong, et.al., Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons., Neuron, 2011, 71

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Slc17a6<tm2(cre)Lowl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5141269
• Slc32a1<tm2(cre)Lowl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5141270

class

http://purl.org/net/cito/citesAsAuthority

• Slc17a6<tm2(cre)Lowl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5141269
• Slc32a1<tm2(cre)Lowl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5141270

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected_Slc17a6<tm2(cre)Lowl>/Slc17a6<+>
  http://metadb.riken.jp/0002169I129S6SvEvTacSlc17a6tm2creLowlSlc17a6Slc17a6tm2creLowlSlc17a6
• abnormal inhibitory postsynaptic currents_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>
  http://metadb.riken.jp/0002945I129S6SvEvTacLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1Slc32a1Leprtm11ChuaSlc32a1tm2creLowl
• increased total body fat amount_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>
  http://metadb.riken.jp/0010024I129S6SvEvTacLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1Slc32a1Leprtm11ChuaSlc32a1tm2creLowl
• increased body weight_Lepr<tm1.2Chua>/Lepr<tm1.2Chua>
  http://metadb.riken.jp/0001260I129C57BL6CBALeprtm12ChuaLeprtm12ChuaLeprtm12Chua
• polyphagia_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>
  http://metadb.riken.jp/0001433I129S6SvEvTacLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1Slc32a1Leprtm11ChuaSlc32a1tm2creLowl
• abnormal circulating glucose level_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>
  http://metadb.riken.jp/0000188I129S6SvEvTacLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1Slc32a1Leprtm11ChuaSlc32a1tm2creLowl
• abnormal nervous system electrophysiology_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>
  http://metadb.riken.jp/0002272I129S6SvEvTacLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1Slc32a1Leprtm11ChuaSlc32a1tm2creLowl
• abnormal inhibitory postsynaptic currents_Lepr<tm1.2Chua>/Lepr<tm1.2Chua>
  http://metadb.riken.jp/0002945I129C57BL6CBALeprtm12ChuaLeprtm12ChuaLeprtm12Chua
• increased circulating insulin level_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>
  http://metadb.riken.jp/0002079I129S6SvEvTacLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1Slc32a1Leprtm11ChuaSlc32a1tm2creLowl
• no abnormal phenotype detected_Slc32a1<tm2(cre)Lowl>/Slc32a1<+>
  http://metadb.riken.jp/0002169I129S6SvEvTacSlc32a1tm2creLowlSlc32a1Slc32a1Slc32a1tm2creLowl
• increased body weight_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>
  http://metadb.riken.jp/0001260I129S6SvEvTacLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1Slc32a1Leprtm11ChuaSlc32a1tm2creLowl
• abnormal inhibitory postsynaptic currents_Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Slc32a1<tm2(cre)Lowl>/Slc32a1<+>,Tg(Pomc1-hrGFP)1Lowl/0
  http://metadb.riken.jp/0002945I129S6SvEvTacFVBNLeprtm11ChuaLeprtm11ChuaSlc32a1tm2creLowlSlc32a1TgPomc1hrGFP1Lowl0Leprtm11ChuaSlc32a1Slc32a1tm2creLowlTgPomc1hrGFP1Lowl