increased intestinal adenocarcinoma incidence_Apc<tm2.1Cip>/Apc<+>,Kras<tm4Tyj>/Kras<+>,Tg(Fabp1-cre)1Jig/0

http://metadb.riken.jp/0002957I129P2OlaHsd129S4SvJaeFVBApctm21CipApcKrastm4TyjKrasTgFabp1cre1Jig0TgFabp1cre1JigApctm21CipApcKrastm4TyjKras

increased intestinal adenocarcinoma incidence_Apc<tm2.1Cip>/Apc<+>,Kras<tm4Tyj>/Kras<+>,Tg(Fabp1-cre)1Jig/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffrey I Gordon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447210
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm2.1Cip>/Apc<+>,Kras<tm4Tyj>/Kras<+>,Tg(Fabp1-cre)1Jig/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Fabp1-cre)1Jig|Apc<tm2.1Cip>|Apc<+>|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased intestinal adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0002957

文献

http://purl.org/net/cito/citesAsAuthority

• Kevin M. Haigis, et.al., Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon., Nature genetics, 2008, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/18372904