increased urine protein level_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0

http://metadb.riken.jp/0002962I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh

increased urine protein level_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• laminin, alpha 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:105382
• transgene insertion 295, Lawrence B Holzman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450360

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lama5<tm1Jhm>|Lama5<tm2Jhm>|Tg(NPHS2-cre)295Lbh

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased urine protein level
  http://purl.obolibrary.org/obo/MP_0002962

文献

http://purl.org/net/cito/citesAsAuthority

• Seth. Goldberg, et.al., Maintenance of glomerular filtration barrier integrity requires laminin alpha5., Journal of the American Society of Nephrology : JASN, 2010, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/20150535